Max-Delbrück-Centrum für Molekulare Medizin
The Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association is an international biomedical research center dedicated to understanding the molecular mechanisms of health and disease with the goal to devise new diagnostics and medicines. The MDC is a member of the Helmholtz Association, Germany's largest scientific organization, and offers an engaging research environment with cutting-edge research infrastructure. Currently, ~1250 employees and ~500 guest scientists work at the Berlin-Buch and Berlin-Mitte campuses. Our diverse workforce is a core strength that inspires creativity and innovation at the MDC.
The MDC is committed to improving human health through transformative biomedical research. Our goal is to pioneer discoveries for preventing, treating, and ultimately curing disease.
As part of a recently awarded ERC starting grant, two fully funded postdoctoral positions are available in the Spatial Proteomics research group headed by Dr. Fabian Coscia at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) in Berlin, Germany.
The Coscia lab is undertaking translational research projects to develop and apply innovative spatial proteomics methods for disease phenotyping. We work at the interface between ultra-sensitive (single-cell) mass spectrometry-based proteomics, multiplex imaging and machine learning driven data analysis.
We have recently co-developed Deep Visual Proteomics, a first-of-its-kind approach combining microscopic cell phenotyping with global and quantitative proteomics (https://www.nature.com/articles/s41587-022-01302-5). The candidate(s) will further develop and apply this new and exciting technology in the field of precision oncology.
As a highly collaborative research group, we closely work with clinical scientists to better understand cancer treatment resistance mechanisms to targeted, chemo or immunotherapies. Our long-term goal is to identify new therapeutic vulnerabilities and improve patient stratification. You will join a young and enthusiastic team of scientists working at the forefront of spatial proteomics for translational research. You will have access to state-of-the-art instrumentation (single-cell mass spectrometry, high-resolution microscopy, NGS) and artificial intelligence guided computational workflows.
Applicants must hold a PhD degree (or equivalent) and are expected to demonstrate excellent achievements in their field of research.
Applicants should have a solid experimental or computational background, a strong publication record as primary author, and excellent communication skills in English. The candidate should further have a strong interest in spatial multi-omics workflows for the profiling of health and disease states.
You have a deep knowledge either in MS-based proteomics, multiplex immunofluorescence microscopy, image data analysis or multi-omics data integration, paired with a passion for translational system biology? Then we would be happy to receive your strong application and get to know you. Instead of a detailed cover letter, we expect you to write a 1-page project proposal demonstrating your intrinsic motivation and how you would envision spatial proteomics approaches can contribute to precision medicine in the future.
You also benefit from:
Postdoctoral researcher for the Heidelberg Institute of Global Health (m/f/d) Heidelberg Vollzeit Universitätsklinikum Heidelberg research associate (m/f/d): 2 years, Prof. Marx - Dauerausschreibung Bochum Vollzeit Ruhr Universität Bochum 4 Postdocs in Neuroscience and related fields (m/f/d) Essen Teilzeit Universitätsklinikum Essen
WiRe Fellowships for international female postdoctoral researchers Münster Vollzeit Westfälische Wilhelms-Universität Münster Doktorand (w/m/d) Leipzig Vollzeit German Centre for Integrative Biodiversity Research (iDiv)