Scientist Membrane Proteins in Berlin bei Nuvisan GmbH
Scientist (f/m/d) Membrane Proteins in Berlin bei Nuvisan GmbH
RESPONSIBILITIES
- The main task is the production of recombinant membrane proteins for biochemical and biophysical assays and for structure determination (X-Ray, CryoEM) in a scientific working group
o Design of expression constructs using in silico tools
o Expression of membrane proteins in different systems (mammalian, insects).
o Purification of membrane proteins.
o Reconstitution of membrane proteins in Nanoparticles (NanoDiscs, Liposomes)
o Biophysical assays with membrane protein to characterize binding of interaction partners
- Evaluation and interpretation of the data obtained, as well as their documentation and presentation
- Written and oral presentations in English for various target groups as well as creating project plans in collaboration with colleagues and customers
- Organization of your own work and the processes in the function including maintenance and further development of the infrastructure (hardware and IT) for the processing of the research projects
- Evaluation and implementation of new technologies for the optimal handling of the given tasks
REQUIREMENTS
- Completed university studies and Ph.D in the fields of biochemistry, biology, chemistry or related fields, 2 years postdoc experience or professional experience, preferably in the field of protein science appreciated.
- Publications as evidence of scientific success.
- Proven experience in purification of membrane proteins (e.g. GPCRs, ion channels, transporter).
- Experience with chromatography systems (e.g. ÄKTA) and processes in the field of protein production.
- Experience in structure determination and data processing with Cryo-EM.
- Experience with Nanobody screening is desirable.
- Experience with biochemical and biophysical assays with membrane proteins (NanoDSF, SPR, CPM, etc.) is desirable.
- Talent for coordination and organization as well as communication and team skills.
WE OFFER
- A permanant employment contract
- Flexible working hours including a modern workplace and the option of working from home (mobile working)
- 30 days annual leave
- Company pension scheme
- Extensive health prevention offers
- Comprehensive introduction and individual training and development
- BVG job ticket and free parking spaces directly on-site
- A dynamic, future-oriented and employee-oriented company, with room for growth and your own ideas
- Interdisciplinary, agile teams with flat hierarchies
- Work on products and services with high social impact