Techn. Assistenz / BTA / CTA Zellkultur / Immunologie / Krebstherapie in Deutschland bei Technische Universität Dresden

The Center for Regenerative Therapies Dresden (CRTD) is an institute of the Center for Molecular
and Cellular Bioengineering (CMCB) and currently hosts over 20 research groups and more than
250 employees. Research at the CRTD focuses on regenerative and stem cell research ranging from
basic research to application in a clinical-translational context. Researchers at the institute develop
new approaches for diagnosis and therapy in the fields of haematology/immunology, diabetes,
neurodegenerative diseases and bone and tissue regeneration. For TUD Dresden University of
Technology diversity is an essential feature and a quality criterion of an excellent university.
Accordingly, we welcome all applicants who would like to commit themselves, their achievements and
productivity to the success of the whole institution.

At CRTD, the Chair of Stem Cell Research with focus on cell-based approaches to regenerative
biomedicine (Prof. Dr. Michael Sieweke) offers a position as

Research Technician / BTA / CTA (m/f/x)
Cell culture / Immunology / Cancer therapy

(subject to personal qualification employees are remunerated according to salary group E 9a TV-L)

starting as soon as possible and initially limited until September 30. 2024. A longer-term employment
is expressly desired (time limitation pursuant to TzBfG). Balancing family and career is an important
issue. The position is generally suitable for candidates seeking part-time employment with at least
75% of the full-time weekly hours. Please indicate the request in your application.

At the Chair for Stem Cell Research with a focus on cell-based approaches in regenerative
biomedicine, the group of Alexander-von-Humboldt Prof. Dr. Michael Sieweke researches the role
of immune cells in regeneration and ageing. We conduct cutting-edge research in macrophage biology
and develop novel cellular therapies for use in cancer and regenerative medicine. We use a broad
range of molecular, genetic, histological and imaging techniques in combination with in vivo and in
vitro model systems. Our mission is to translate ground-breaking research results into effective
therapies that can benefit patients as soon as possible. To accelerate this process, we are pursuing
the spin-off of a start-up company, which is funded by the BMBF/GoBio-Initial programme. Within the
framework of this project, we are looking for support for the step-by-step development and
implementation of a macrophage-based therapy against solid tumours.

Tasks: You will play a crucial role in the development of new cell therapy products for cancer
immunotherapy. Your tasks include the scaling, automation and optimisation of cell culture processes
with modern equipment, as well as technical support in the planning, execution and analysis of cell
biological as well as immunological work, development and optimisation of new protocols and
application of techniques such as qPCR, ELISA, flow cytometry, immunofluorescence, etc.
Documentation, evaluation and presentation of experimental procedures and research results in
English.

Requirements: We are looking for a highly qualified and motivated research technician with
experience in cell culture, immunological and possibly animal experimental work to join our research
and development team.

• You have completed vocational training as a biological-technical assistant (BTA), chemical-

technical assistant (CTA) or a as biological/chemical laboratory technician with equivalent
knowledge and experience and have several years of professional experience.

• You have very good knowledge and practical experience in sterile cell culture and the

performance of immunological assays such as flow cytometry, ELISA and functional tests of
immune cells.

• You have a sound knowledge of English and enjoy constantly improving this knowledge due

to the international nature of the working group and the institute.

• You show a high degree of responsibility, independence and motivation.
• Your open-minded nature makes you a valued team player who enjoys scientific and

animal experimen