Universitätsklinikum Köln
Have we awakened your interest? Please submit your application (including a detailed CV, list of publications, at least two letters of reference and a brief statement of research interests) online.
What we have to offer is a vibrant work environment with strong affiliation within the FOR5504 research unit. This offers the opportunity of mentoring and interactions with several global scientific leaders in their respective fields. In addition, the highly collaborative research environment in Cologne provides us with access to state-of-the-art core facilities, including the entire OMICS-spectrum and imaging techniques.
Working at the University Hospital Cologne and the Medical Faculty means helping to shape the future - the future of medicine, of patients and, of course, your own future. You benefit from 60 clinics and institutes as well as numerous other departments and facilities and more than 12,000 jobs. The Faculty of Medicine of the University of Cologne and the University Hospital Cologne assume important social tasks in research, teaching and patient care. A close network with many university and non-university partners guarantees an internationally successful science and the excellent education of our students.
As part of DFG-funded, research unit FOR 5504 on ‘Physiological causes and consequences of genome instability’ we are looking for a full-time (38.5 hrs/week), highly qualified and passionate candidate (f/m/x) for a postdoctoral position (TVL-E13, 100%) in the affiliated subproject ‘The impact of chronic genome instability on tissue homeostasis and how reduced diet alleviates DNA damage-driven functional deterioration’ in the research group of Prof. Jan Hoeijmakers within the CECAD research center, Cologne, Germany (department: Institute for Genome Stability in Aging and Disease, Prof. Schumacher).
The subproject aims at gaining a completer insight of the impact of genome instability (GI)-related transcriptional stress (TS) on systemic aging and underlying mechanisms. The group further aims to characterize the genomic, transcriptional and metabolic burden of increasing GI and TS in different postmitotic tissues and to examine the effects of dietary-restriction-induced metabolic redesign.
To achieve this, state-of-the-art mammalian GI models will be employed in combination with multi-OMICS- and high-throughput sequencing approaches, and in-vitro and ex-vivo techniques.
Selected publications:
Postdoc/ Immunologist (f/m/x) – CECAD (KHS-32355) Köln Vollzeit Universitätsklinikum Köln Medical Data scientist (f/m/x) for biomedical informatics and data science Köln Vollzeit Universitätsklinikum Köln AöR PhD student (f/m/x) Köln Vollzeit Universitätsklinikum Köln AöR
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