PhD student positions in Healthy Aging Research Biochemistry & Bioinformatics in Berlin-Mitte bei Charité

Working at the Charité

We are pursuing research on the biochemical or big-data-driven basis of longevity regulation to identify novel therapeutic options to prevent and cure age-related diseases like obesity, diabetes, neurodegeneration and cancer.

We aim to identify novel promoters of healthy aging by (i) characterizing previously identified candidate genes for physiological and pathological aging, as well as by (ii) analysing preexistent big-data sets and cohorts to identify modifiers of human over-all and disease-specific mortality, to ultimately identify targets as well as pre-clinical and clinical approaches to facilitate better health at higher age.

The PhD degree can be obtained at Humboldt University Berlin, or at Charité University Medicine Berlin.

Job overview

• Designing and performing experiments on aging and age-related diseases in vitro, in vivo and in silico.
• Using diverse experimental methods, including human cell culture, genome editing, molecular biology, RNA analyses, fluorescence microscopy, recombinant protein expression/purification, in vitro biochemical assays
• Performing experiments in model-organisms (C. elegans, mice)
• Generating and analysing transcriptomic/metabolomics/proteomics datasets
• Analysing big-data sets and human cohorts regarding mortality risks and pharmacological and environmental modulators thereof
• Communicating research outcomes at relevant international conferences and in peer-reviewed journals

We are looking for

• M.Sc. or equivalent degree in Biochemistry, Bioinformatics, Biology, Cell/Molecular Biology, Bioengineering, Genetics, Medical Biology, or a related field
• Dedication to research on ageing and age-related disease
• Experience with or interest in bioinformatics is essential (position 1) or advantageous position 2)
• Interest and/or expertise in working with biological systems (cells, C. elegans, mice)
• Scientific curiosity and motivation to perform scientifically rigorous experimental work
• Appreciation for interdisciplinary work and proactive drive to collaborate across disciplines
• Ability to work independently as well as part of a team, excellent organizational skills and high reliability
• Strong verbal and written communication skills in English (i.e. German not required)

Advantages at the Charité

• A relaxed but highly professional collaboration in a familiar, motivated, interdisciplinary team
• A future-oriented, varied and challenging job with a high degree of personal responsibility and personal freedom of action
• Multicultural team events, well-structured onboarding with nice colleagues
• Extensive free continuing education and training opportunities up to and including university studies
• Discounts on many employee offers for shopping, travel, sports
• Our company pension scheme provides our employees with additional security in old age
• Reconciliation of private life, family and work; we are a certified family company - Here you can find more information

Job Information

• Pay group E13 according to TVöD- VKA- K. The grouping takes place under consideration of the qualification, the respective experience level is calculated from the completed professional years. The annual salary (gross) is given for a full-time position without annual bonus, allowances and additional services.
• The working time is 25,4 hours per week
• The contract is limited to 24 month period.
• At our company 30 days of vacation are standard
• The application deadline is on: 31.10.2023
• Reference number: 1200

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