Scientific Assistant (PhD student) Center for Stroke Research Berlin - DM.117.23a in Berlin-Mitte bei Charité

Arbeiten an der Charité

Charité was once again voted the best hospital in Germany because our more than 20.900 employees do an excellent job every day – both in patient care and in research, teaching and administration. Patients from all over the world rely on the expertise of our staff as well as on state-of-the-art diagnostics and treatment methods.

You make the difference

Die Stelle im Überblick

In this project, you will:

• Use human induced pluripotent stem cells (hiPSC) for the generation of human neurons and 3D organoid models of the brain
• Investigate mitochondrial mechanisms of neurodegeneration, and the relation of cell death, energy metabolism and autophagy
• Work with models of neuronal damage / stroke
• Perform multidimensional microscopy, high content microscopy, multi-OMICS, and corresponding image / data and analyses
• Perform bioinformatics analyses of transcriptional profiles of neuronal populations (~30% of total work)

Scientific employees are given sufficient time for their own scientific work in accordance with their employment relationship.

Danach suchen wir

• You have recently completed your university studies in the life sciences, preferably with a focus on cell biology.
• Knowledge in working with primary cells or stem cells is an advantage, but not a prerequisite.
• You are familiar with fluorescence microscopy, and standard techniques in cell biology, molecular biology and biochemistry.
• You are interested in and willing to familiarize yourself with the methods of automated microscopy (high content analysis) and multidimensional image analysis and data analysis (R or Python), as well as with basic research in the clinical neurosciences.
• You are interested and willing to collaborate in an international research environment and to closely interact with the Buchan Lab at Oxford University and spend research time at Oxford University.

Candidates are expected to show a high level of independence. Exact documentation of all work, motivation to establish new techniques, prepare data analyses, project reports and manuscripts independently, very good knowledge of the English language, and excellent computer skills are expected. Applications should be directed to Alastair Buchan and Philipp Mergenthaler by Email. Please include a cover letter describing your past research experience and potential future research interests. Please provide all necessary documents (transcripts of record, references, etc.) as a single PDF file.

Das bringt die Charité mit

• A relaxed but highly professional collaboration in a familiar, motivated, interdisciplinary team
• A future-oriented, varied and challenging job with a high degree of personal responsibility and personal freedom of action
• Multicultural team events, well-structured onboarding with nice colleagues
• Extensive free continuing education and training opportunities up to and including university studies
• Discounts on many employee offers for shopping, travel, sports
• Our company pension scheme provides our employees with additional security in old age
• Reconciliation of private life, family and work; we are a certified family company - Here you can find more information

Informationen zur Stelle

• Pay grade E13 according to TVöD- VKA- K. The grouping takes place under consideration of the qualification and the personal requirements
• Part-time-employment with 29,35 hours per week
• A future-oriented, varied and challenging job with a high level of personal responsibil