Computational PhD Student in cancer genomics bei Universitätsklinikum Köln AöR

Universitätsklinikum Köln AöR

as soon as possible
part-time (29 hours/week); limited for 3 years according to WissZeitVG (Third-party funded project)
Your salary will be based on TV-L
» Your tasks

You will be part of the DFG-funded SFB1588 consortium “Decoding and Targeting Mechanisms of Neuroblastoma Evolution” where you will develop novel algorithms and tools for investigating the origin, evolution and re-integration of extrachromosomal circular DNAs. For this you will work closely with our clinical collaborators at the University Hospital Cologne and at the Charité Berlin, as well as with an interdisciplinary and collaborative team of bioinformaticians and experimentalists, on a project with strong translational potential.

» Your Profile

Ideal candidates will have a Masters degree in Bioinformatics, Physics, Mathematics, Computer Science or a related field, and a strong interest in quantitative and genetics research. Prior experience in method development for cancer genomics is ideal. Successful candidates will show a strong work ethic and should be enthusiastic about working in a highly interdisciplinary environment. Excellent communication skills and the ability to work in a team are required.

For further reading and our recent works see:
Kaufmann et al. 2022, Genome Biology

Watkins et al. 2020, Nature

Stöber et al. 2023, bioRxiv

» Our Offer
A varied job in a highly interesting and challenging research topic
A fair working environment with appreciative cooperation
Possibility to develop side projects according to personal interests
Internal and external training opportunities
Flexible working time models to support family life
Occupational health management offers

We offer a competitive salary according to German E13 TVL 75%. Contracts are limited to 3 years with the possibility of prolongation. Applications should be submitted online here. For inquiries, please email roland.schwarz@uni-koeln.de. The positions are to be filled as soon as possible; applications will be considered initially until November 26.

» Your future with us

Working at the University Hospital Cologne and the Medical Faculty means helping to shape the future - the future of medicine, of patients and, of course, your own future. You benefit from 59 clinics and institutes as well as numerous other departments and facilities and more than 10,000 jobs. The Faculty of Medicine of the University of Cologne and the University Hospital Cologne assume important social tasks in research, teaching and patient care. A close network with many university and non-university partners guarantees an internationally successful science and the excellent education of our students.

» Your future in detail

Our computational group is interested in understanding the role of chromosomal instability, somatic copy number alterations (SCNA) and chromatin structure in cancer evolution. We develop and apply algorithms for inferring and simulating cancer evolution and for haplotype reconstruction and phasing in close collaboration with our clinical and experimental partners. We are part of several national and international consortia, such as the ICGC-ARGO, TRACERx, and SATURN3 consortia. Part of our group is also based at the Berlin Institute for the Foundations of Learning and Data (BIFOLD) at the TU Berlin. There will be ample opportunities for visits and exchanges between our partner sites.

Applications from female candidates are expressly welcome and will be given priority in the event of equal suitability, competence and professional performance.

People with disabilities are welcome to apply and will be treated preferentially in the event of equal suitability and qualification.

Contact:
Prof. Roland Schwarz
https://www.uk-koeln.de
Application deadline: 26.11.2023

Postal address:
Universitätsklinikum Köln AöR
PA30
Geschäftsbereich Personal