PostDoc position immunology bei Universitätsklinikum Freiburg

PostDoc position immunology (m/f/d) bei Universitätsklinikum Freiburg

Universitätsklinikum Freiburg

What are you waiting for? The Department of Rheumatology and Clinical Immunology and Center for Chronic Immunodeficiency, in the group of Prof. Dr. Marta Rizzi, is looking for you are available as per February 1st, 2024

PostDoc position immunology (m/f/d)

The projects require both wet-lab and bioinformatics analysis. Our group studies human B-lymphocytes development, maturation and activation in physiological and pathological conditions. Our lab has unique expertise in in-vitro modelling of early and late human B cell development that we use: to uncover mechanisms of disease in monogenic defects leading to autoimmunity; to study the B cell function in more complex rheumatological diseases; to assess the specific impact on human B lymphocytes of novel targeted therapies. (https://www.uniklinik-freiburg.de/rheuim/wissenschaft-und-forschung/ag-rizzi.html).

The research focuses of the position will be: single cell analysis of developmental pathways in early and late B cell development; B cell repertoire analysis, development of 3D culture systems to model development and cell-cell interactions, integration and outcome of signaling in B cells.

We offer:

work at the interface of translational medicine and basic research
a well-equipped, state-of-the-art research environment within the University Medical Center Freiburg
a large international network of collaborators and interdisciplinary projects
the opportunity to learn and apply a variety of modern methods in cell-, protein- and molecular biology
an enjoyable laboratory atmosphere with intensive mentorship
Involvement in student teaching and mentoring

Required skills:

Ph.D. in biology or in a related field with an excellent publication record OR
PhD in computer science, mathematics, physics, bioinformatics, computational biology or similar background with focus on bioinformatics or data science. Alternatively, a M.Sc. or equivalent qualification with complementary years of relevant experience.
hands-on experience with workflow development and -omics data (single cell RNA seq, transcriptomics, B cell receptor repertoire) analysis using open source software and algorithms
Experience in state-of-the-art molecular biology and/or biochemistry
Experience in working with primary human cells and cell lines (isolation, cultivation, stimulation, 3D cultures)
creative innovative thinking
intrinsic motivation, high precision of work and the ability to conduct independent research
Interest in working in an interdisciplinary environment
proven English presenting and writing skills

The position is limited to 36months.

Please send applications including the usual documentation via the "Apply Now" button.

For further inquiries, please contact:

Prof. Marta Rizzi - Group Leader

+49-761/270-62170

General information: Salary is assigned according to a pay scale. Unless prevented by operational or legal reasons, full-time positions are generally open to those wishing to job share. Where two candidates are equally suitable for a post, severely disabled candidates are given priority. Employment decisions are made by the Personnel Department.